Interested in learning even more about the science of buffering local anesthetics?
View the following articles and studies below! These are the articles that are referenced in the video, Science of Buffering – Anutra Medical and on our webpage The Science of Buffering.
Key Studies for the Science of Buffering
- Adding sodium bicarbonate to lidocaine enhances the depth of epidural blockade. | Curatolo M1, Petersen-Felix S, Arendt-Nielsen L, Lauber R, Högström H, Scaramozzino P, Luginbühl M, Sieber TJ, Zbinden AM.
- Adjusting the pH of lidocaine for reducing pain on injection. | Cepeda MS1, Tzortzopoulou A, Thackrey M, Hudcova J, Arora Gandhi P, Schumann R.
- Alkalinization of local anesthetics. Which block, which local anesthetic? | Capogna G1, Celleno D, Laudano D, Giunta F.
- Faster onset and more comfortable injection with alkalinized 2% lidocaine with epinephrine 1:100,000 | Malamed SF, Tavana S, Falkel M.
- The Influence of CO2 and pH on Local Anesthetic Action | Richard F. H. Catchlove
- Neutralized lidocaine with epinephrine for local anesthesia–II. | Stewart JH1, Chinn SE, Cole GW, Klein JA.
- Sodium Bicarbonate Attenuates Pain on Skin Infiltration with Lidocaine, with or without Epinephrine | McKay, Warren MD; Morris, Richard MBBS, FFARACS; Mushlin, Phillip MD, PhD
Additional Studies on the Science of Buffering for Further Reading